By Dan Jones
As diagnoses of autism spectrum disorder rise, the need for effective therapies has increased in urgency.
They began by genetically engineering mice so that they lacked the gene Eif4ebp2. The 4E-BP2 protein that this produces suppresses the translation of certain messenger RNAs, so knocking out Eif4ebp2 allows the proteins that these mRNAs produce to be synthesized at above normal levels.
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